PR – HCS Pharma extends its 3D cell culture range BIOMIMESYS® with BIOMIMESYS® Brain

Following the success of BIOMIMESYS® range of products, which accurately and physiologically reproduces the microenvironment of liver, adipose and cancerous tissues, HCS Pharma is expanding its product range with BIOMIMESYS® Brain, an exclusive and innovative system for the 3D cell culture of neuronal cells. BIOMIMESYS® technology, provided “ready-to-use”, is easy Read more…

CP – HCS Pharma complète sa gamme de culture cellulaire en 3D BIOMIMESYS® avec BIOMIMESYS® Brain

Après le succès de la gamme BIOMIMESYS® reproduisant de manière précise et physiologique le microenvironnement du foie, des tissus adipeux et des tissus cancéreux, HCS Pharma étend sa gamme avec BIOMIMESYS® Brain, un système exclusif et innovant permettant la culture cellulaire en 3D de cellules neuronales. La technologie BIOMIMESYS®, fournie Read more…

Elastin‐derived peptides: Matrikines critical for glioblastoma cell aggressiveness in a 3‐D system

Source : Elastin‐derived peptides: Matrikines critical for glioblastoma cell aggressiveness in a 3‐D system Abstract In the most common primary brain tumors, malignant glioma cells invade the extracellular matrix (ECM) and proliferate rapidly in the cerebral tissue, which is mainly composed of hyaluronan (HA) along with the elastin present in Read more…

Three Dimensional Tumor Engineering by Co-Culture of Breast Tumor and Endothelial Cells Using a Hyaluronic Acid Hydrogel Model

Source : Three Dimensional Tumor Engineering by Co-Culture of Breast Tumor and Endothelial Cells Using a Hyaluronic Acid Hydrogel Model Abstract Besides tumor cells, the microenvironment harbors a variety of host-derived cells. To date, the most successful tissue engineering approaches have employed methods that recapitulate the composition, architecture and/or chemical Read more…

Survival of cord blood haematopoietic stem cells in a hyaluronan hydrogel for ex vivo biomimicry

Source : Survival of cord blood haematopoietic stem cells in a hyaluronan hydrogel for ex vivo biomimicry Abstract Haematopoietic stem cells (HSCs) and haematopoietic progenitor cells (HPCs) grow in a specified niche in close association with the microenvironment, the so‐called ‘haematopoietic niche’. Scaffolds have been introduced to overcome the liquid Read more…

Reticulated hyaluronan hydrogels: a model for examining cancer cell invasion in 3D

Source : Reticulated hyaluronan hydrogels: a model for examining cancer cell invasion in 3D Abstract The extracellular polysaccharide hyaluronan (HA) controls cell migration, differentiation and proliferation, and contributes to the invasiveness of human cancers. The roles of HA cell surface receptors and hyaluronidases (HAses) in this process are still controversial. Read more…

Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity

Source : Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity Abstract The extracellular polysaccharide hyaluronan (HA) controls cell migration, differentiation and proliferation, and contributes to the invasiveness of human cancers. In order to investigate the sensitivity of cancer cells to antimitotic agents, we developed a cross-linked Read more…