Reticulated hyaluronan hydrogels: a model for examining cancer cell invasion in 3D

Source : Reticulated hyaluronan hydrogels: a model for examining cancer cell invasion in 3D Abstract The extracellular polysaccharide hyaluronan (HA) controls cell migration, differentiation and proliferation, and contributes to the invasiveness of human cancers. The roles of HA cell surface receptors and hyaluronidases (HAses) in this process are still controversial. Read more…

Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity

Source : Hyaluronan hydrogel: An appropriate three-dimensional model for evaluation of anticancer drug sensitivity Abstract The extracellular polysaccharide hyaluronan (HA) controls cell migration, differentiation and proliferation, and contributes to the invasiveness of human cancers. In order to investigate the sensitivity of cancer cells to antimitotic agents, we developed a cross-linked Read more…